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Estudios sobre las propiedades del arándano rojo americano.

En 1998, un grupo de investigadores identificó, mediante fraccionamiento biodirigido, las proantocianidinas (PAC) o taninos condensados, como los constituyentes responsables de la actividad antiadherente en el arándano rojo americano.

Ya en el siglo XXI y hasta la actualidad, se han multiplicado los ensayos clínicos y farmacológicos a todos los niveles, lo que es un claro indicador del interés científico que el extracto de arándano rojo americano ha despertado en todo el mundo.

 

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Anti-Inflammatory Effects of Zingiber Officinale in Type 2 Diabetic Patients

Purpose: Low-grade inflammation, a common feature in type 2 diabetes (DM2), causes some chronic complications in these patients. The present study was aimed to evaluate the effects of ginger (Zingiber officinale) on pro-inflammatory cytokines (IL-6 and TNF-α) and the acute phase protein hs-CRP in DM2 patients as a randomized double-blind placebo controlled trial. Methods: A total of 64 DM2 patients randomly were assigned to ginger or placebo groups and received 2 tablets/day of each for 2 months. The concentrations of IL-6, TNF-α and hs-CRP in blood samples were analyzed before and after the intervention. Results: Ginger supplementation significantly reduced the levels of TNF-α (P = 0.006), IL-6 (P = 0.02) and hs-CRP (P = 0.012) in ginger group in comparison to baseline. Moreover, the analysis of covariance showed that the group received ginger supplementation significantly lowered TNF- α (15.3 ± 4.6 vs. 19.6 ± 5.2; P = 0.005) and hs-CRP (2.42 ± 1.7 vs. 2.56 ± 2.18; P = .016) concentrations in comparison to control group. While there were no significant changes in IL-6 (7.9 ± 2.1 vs. 7.8 ± 2.9; P > .05). Conclusion: In conclusion, ginger supplementation in oral administration reduced inflammation in type 2 diabetic patients. So it may be a good remedy to diminish the risk of some chronic complications of diabetes.

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DEFINICIÓN

Hoja seca, entera o cortada, de Cynara cardunculus L. (sin. C. scolymus L.).

Contenido: como mínimo 0,8 por ciento de ácido clorogénico (C16H18O9; Mr 354,3) (droga desecada).

IDENTIFICACIÓN

A. La hoja entera puede alcanzar 70 cm de longitud y 30 cm de anchura. El limbo está profundamente lobulado en la parte superior, hasta 1-2 cm del pecíolo de cada

lado, y se vuelve pinnado en la parte inferior de la hoja; todos los segmentos tienen bordes marcadamente dentados y se estrechan en el ápice. No se observan

espinas. El haz es de color verde con un fino vello blanquecino, mientras que el envés es de color verde pálido o blanco y densamente tomentoso con largos pelos

enmarañados. El pecíolo y las..

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Abstract

Background: Zingiber officinale R. rhizome (ginger) is a popular spice that has traditionally been used to combat the effects of various inflammatory diseases. The aim of this study was to evaluate the effects of ginger on pain relief in primary dysmenorrhea.

Method: This was a randomized, controlled trial. The study was based on a sample of one hundred and twenty students with moderate or severe primary dysmenorrhea. The students were all residents of the dormitories of Shahed University. They were randomly assigned into two equal groups, one for ginger and the other for placebo in two different treatment protocols with monthly intervals. The ginger and placebo groups in both protocols received 500 mg capsules of ginger root powder or placebo three times a day. In the first protocol ginger and placebo were given two days before the onset of the menstrual period and continued through the first three days of the menstrual period. In the second protocol ginger and placebo were given only for the first three days of the menstrual period. Severity of pain was determined by a verbal multidimensional scoring system and a visual analogue scale.

Results: There was no difference in the baseline characteristics of the two groups (placebo n = 46, ginger n = 56). The results of this study showed that there were significant differences in the severity of pain between ginger and placebo groups for protocol one (P = 0.015) and protocol two (P = 0.029). There was also significant difference in duration of pain between the two groups for protocol one (P = 0.017) but not for protocol two (P = 0.210).

Conclusion: Treatment of primary dysmenorrhea in students with ginger for 5 days had a statistically significant effect on relieving intensity and duration of pain.

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